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2nd International Symposium on Merkel Cell Carcinoma

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Add to Calendar 2nd International Symposium on Merkel Cell Carcinoma 4/25/2022 7:00:00 AM 4/26/2022 4:00:00 PM America/Los_Angeles For More Details: https://uw.cloud-cme.com/MCC-2022 Description: The 2nd International Symposium on Merkel Cell Carcinoma (MCC) is designed to explore emerging data that may allow improvements in understand the basic biology that drives this disease, clinical guidelines, and to develop innovative approaches. Updates from the most recent clinical guidelines as well as emerging data regarding MCC biology are highlighted in plenary sessions.The educational purpose of this symposium is to dissem... Graduate Hotel false MM/DD/YYYY


Date & Location
Monday, April 25, 2022, 7:00 AM - Tuesday, April 26, 2022, 4:00 PM, Graduate Hotel

Credits
AMA PRA Category 1 Credits™ (12.75 hours), Non-Physician (12.75 hours)

Overview

The 2nd International Symposium on Merkel Cell Carcinoma (MCC) is designed to explore emerging data that may allow improvements in understand the basic biology that drives this disease, clinical guidelines, and to develop innovative approaches. Updates from the most recent clinical guidelines as well as emerging data regarding MCC biology are highlighted in plenary sessions. The educational purpose of this symposium is to disseminate emerging data and to advance MCC research through a stimulating and collaborative meeting.

The need for clinicians to continuously stay abreast of developments and current standards of care in the field of MCC is challenging because it is so rapidly evolving. Many clinicians are not familiar with how MCC differs from other skin cancers in its optimal management.

This activity will offer comprehensive reviews of the established standards of care and recent clinical advances in the field of MCC management, national cancer guidelines, and treatment recommendations in various clinical settings. 


Objectives
Upon completion of this activity, attendees should be able to:

  1. Address the outstanding questions in MCC basic biology and how they can lead to improvements in clinical care.
  2. Identify the current clinical MCC biomarkers of disease burden and how to interpret those.
  3. Review and discuss the updated national MCC clinical guidelines.

Registration
 In-person, All Learners (unavailable) $300.00 USD
 In-person, Resident/Fellow* (unavailable) $200.00 USD
 Virtual/Online Attendance Only - all degrees $200.00 USD

*Resident/Fellow rate requires written confirmation of current status. Failure to provide required documentation may result in an additional balance owed.  All registration levels are approved for AMA PRA Category 1 Credits™.

UPDATE 4/7/22: In-Person attendance is at capacity - onsite registration will not be available.

Registration has CLOSED effective Wednesday, April 20, 2022 at 5pm Pacific Time for all registration types.

Continuing Medical Education at the University of Washington is a self-sustaining unit and does not depend on or receive public monies in support of its educational efforts. The course fees are estimated to cover transcript of AMA PRA Category 1 Credits™, access to online instruction materials, course logistics, food and beverage (including alcohol), faculty planning and salaries.

If you have not received confirmation prior to the course start, please contact the CME office at [email protected]. Continuing Medical Education will not be responsible for expenses incurred by an individual who is not confirmed.

Per UW CME policy, you are not considered to be registered for the course until full payment has been received. Unpaid orders do not "reserve" spots for conferences or workshops.

COVID-19 SAFTEY MEASURES

Following CDC guidance for physical distancing, in-person attendance capacity will be reduced. For those preferring to attend in-person, early registration is recommended. In order to ensure the health and safety of the University campus community and the public, masks are required to be worn, regardless of vaccination status.

Letter from the Chair

CANCELLATION AND REFUND POLICY

The Office of Continuing Medical Education must receive written notification of your cancellation by March 25, 2022. A $75.00 processing fee will be deducted from refund requests received by this date. No refunds will be issued following March 25, 2022. 

The Office of Continuing Medical Education reserves the right to cancel this course twenty (20) days prior to the course date when a minimum enrollment is not met or for other reasons that prevent the University from holding the course. Each registrant will be notified by written notification and a full refund. The University of Washington is not responsible for any other costs incurred. Contact the CME Office with questions via email: [email protected].


Additional Information

WHO SHOULD ATTEND
Healthcare providers including MDs, DOs, PhDs, other healthcare professionals, and scientists interested in MCC.

CALL FOR ABSTRACTS
Abstracts are being accepted for this activity. Outstanding abstracts will be selected for short oral presentations and receive complimentary registration to the symposium. Abstracts may also be selected for poster submissions. Please review the abstract submission information and provide additional required information here: https://www.surveymonkey.com/r/MCC2022_Abstracts SUBMISSION DEADLINE: February 15, 2022

ONLINE CONFERENCE SYLLABUS
Instruction materials will be available online at uwcme.org (for conference registrants only) beginning April 18, 2022. Content will be recorded and available to attendees for educational purposes. Attendees will be notified when recordings are available, approximately 4-6 weeks after course completion. CME credit is available only for attending the live webinar; no credit is available for watching the recorded lectures. Webinar registrants will receive instructions by email prior to the course.

SYSTEM REQUIREMENTS FOR VIRTUAL ATTENDANCE
Prior to the start, please ensure you have the appropriate system requirements to participate in the webinar. More information about the recommended technical requirements is below. No refunds will be available for technical issues not controlled by UW CME. Reliable internet access is necessary. It is strongly recommended that you test your Zoom connection prior to this activity.

Minimum browser requirements for successful access and completion of this activity are as follows:

  • Chrome version 70.0 or newer, or Firefox version 63.0 or newer.
  • Internet Explorer and Safari are not recommended with the UW CME website.
  • You may use any browser to view the Zoom webinar.

COPYRIGHT
The content is the property of the University of Washington and is protected by law, including but not limited to copyright and trademark statutes. This content is for educational purposes only and may not be used for commercial gain. The University of Washington reserves the right to revise or withdraw content from use. Redistribution of this content is strictly prohibited.

SPECIAL SERVICES
The University of Washington reaffirms its policy of equal opportunity regardless of race, color, creed, religion, national origin, sex, sexual orientation, age, marital status, disability, or status as a disabled veteran or Vietnam era veteran in accordance with University policy and applicable federal and state statutes and regulations. The University of Washington is committed to providing access and reasonable accommodation in its services, programs, activities, education and employment for individuals with disabilities. To request disability accommodation, contact the Disability Services Office at least ten (10) days prior to the start of the conference at 206-543-6450 (voice), 206-543-6452 (TTY), 206-685-7264 (fax), or [email protected]. 


Accreditation

Accreditation with Commendation: The University of Washington School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The University of Washington School of Medicine designates this live activity for a maximum of 12.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.




Keywords:

Graduate Hotel (Conference Hotel)

The Graduate Hotel is offering a special rate for $139 USD per night; Last Day to Book: March 29, 2022

Courtyard Marriott, Seattle (Northgate) 

Courtyard is offering a special rate for $139 USD per night; Last Day to Book: April 14, 2022

 

Travel Advisory: In-Person Attendance

For those who plan to attend in-person, please familiarize yourself with the travel requirements set forth by the CDC. Domestic and International travelers can find their requirements on the CDC website HERE.

If travel restrictions prohibit you from attending in-person after purchase, please contact the CME office by email at [email protected] to modify your registration to virtual attendance. The deadline to switch to virtual is April 15, 2022.

Transit Options

Worried about getting to the U District? There's a brand new light rail station outside our location! Travel directly from Sea-Tac International Airport to our front door. Take the 1 Line, and step off at "U District Station." More information about Light Rail HERE.

Traveling by Uber/Lyft? The address for the Graduate Hotel is: 4507 Brooklyn Ave NE, Seattle, WA 98105

Mitigation of Relevant Financial Relationships


University of Washington School of Medicine adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including faculty, planners, reviewers or others are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Christopher Barker, MD
Associate Attending Radiation Oncologist/Associate Attending Member, Department of Radiation Oncology
Memorial Sloan Kettering Cancer Center
New York, NY
Jurgen Becker, MD, PhD
Professor & Department Head, Translational Skin Cancer Research
University of Duisburg-Essen
Duisburg, Germany
Faculty Photos
Shailender Bhatia, MD
Professor
Department of Medicine, Hematology and Oncology
Professor, Clinical Research Division (FHCRC)
Physician (FHCRC)
Director, Melanoma and Renal Cancer Team, Fred Hutch
University of Washington | Fred Hutchinson Cancer Research Center
Seattle, WA
Astrid Blom, MD
Dermatology Department
Ambroise Pare Hospital
Boulogne-Billancourt, France
Isaac Brownell, MD, PhD
Head, Cutaneous Development & Carcinogenesis Section; Senior Investigator, Dermatology Branch
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Bethseda, MD
Sunandana Chandra, MD, MS
Medical Oncologist
Northwestern University
Chicago, IL
Sandra D'Angelo, MD
Medical Oncologist
Memorial Sloan Kettering Cancer Center
New York, NY
James A. DeCaprio, MD
Professor of Medicine, Harvard Medical School; Chief, Division of Molecular and Cellular Oncology, Dana-Farber Cancer Institute
Boston, MA
Andrezj Dlugosz, MD
Poth Professor of Cutaneous Oncology Associate Director for Basic Science Research, Rogel Cancer Center Associate Chair for Research, Dermatology Professor, Dermatology Professor, Cell and Developmental Biology
University of Michigan
Ann Arbor, MI
Denise Galloway, PhD
Research Professor, Department of Microbiology (UW); Interim Director, Human Biology Division (FHCRC)
University of Washington (UW)/Fred Hutchinson Cancer Research Center (FHCRC)
Seattle, WA
Sine Hadrup, PhD
Technical University of Denmark
Kongens Lyngby, Denmark
Paul Harms, MD, PhD
Associate Professor of Pathology and Dermatology
University of Michigan
Ann Arbor, MI
Natasha Hill, PhD
National Institute of Arthritis and Musculoskeletal and Skin Diseases
Bethesda, MD
Saumya Jani, B.S.
M3D PhD Program
University of Washington
Seattle, WA
Derin Keskin, PhD
Lead Scientist Dana Farber Cancer Institute. Associate Professor Denmark Technical Institute
Dana Farber Cancer Institute, Harvard Medical School
Cambridge, MA
Emily Keung, MD
Assistant Professor of Surgery, Department of Surgical Oncology, Division of Surgery
University of Texas MD Anderson Cancer Center
Houston, TX
Sungjune Kim, MD, PhD
Moffitt Cancer Center
Tampa, FL
David Koelle, MD
Professor, Division of Allergy and Infectious Diseases
University of Washington
Seattle, WA
Kyle Lauck, MD, Resident Physician (PGY-1)
UT Health McGovern Medical School
Houston, TX
Evan Lipson, MD
Associate Professor, Medical Oncology
Johns Hopkins University
Baltimore, MD
Mackenzie Martin, BA
Postbaccalaureate Fellow, Cutaneous Development and Carcinogenesis Section
National Institute of Arthritis and Musculoskeletal and Skin Diseases
Bethesda, MD
David Miller, MD, PhD, FAAD
Director, Center for Merkel Cell Carcinoma Co-Director, NMSC Multi-Disciplinary Clinic Department of Medicine, Division of Hematology/Oncology Department of Dermatology Massachusetts General Cancer Center Instructor of Medicine and Dermatology, Harvard Medical School
Boston, MA
Ata Moshiri, MD, MPH
Assistant Professor, Division of Dermatology (UW); Physician (UW & SCCA)
University of Washington/Seattle Cancer Care Alliance
Seattle, WA
Faculty Photos
Paul Nghiem, MD
Professor and Endowed Chair, Division of Dermatology; Adjunct Professor, Department of Laboratory Medicine & Pathology
University of Washington
Seattle, WA
UPENDRA PARVATHANENI, MBBS, FRANZCR
Professor, Department of Radiation Oncology; Adjunct Professor, Dermatology
University of Washington
BELLEVUE, WA
Abbas Rattani, MD
Resident Physician
University of Louisville
Louisville, KY
Nick Salisbury, PhD
Postdoctoral Research Fellow
Fred Hutchinson Cancer Research Center
Seattle, WA
Mahtab Samimi, MD, PhD
Onco-dermatologist
University Hospital of Tours
Tours, France
Sophia Shalhout, PhD
Cutaneous Oncology Research Fellow
Massachusetts General Hospital, Harvard Medical School
Boston, MA
Vernon K. Sondak, MD
Chair, Department of Cutaneous Oncology Richard M. Schulze Family Foundation Distinguished Endowed Chair in Cutaneous Oncology
Moffitt Cancer Center
Tampa, FL
Lisa Tachiki, MD
ACGME Fellow, Division of Hematology
University of Washington
Seattle, WA
Margot Tesselaar, MD
Antoni van Leeuwenhoek Netherlands Cancer Institute
Amsterdam, Netherlands
Suzanne Topalian, MD
Professor of Surgery & Oncology, Associate Director, Bloomberg Kimmel Institute for Cancer Immunotherapy
Johns Hopkins University
Baltimore, MD
Richard Tothill, PhD
Associate Professor; Rare Disease Oncogenomics
University of Melbourne
Melbourne, Australia
Kenneth Tsai, MD, PhD
Vice Chair, Reasearch & Pathology
Moffitt Cancer Center
Tampa, FL
Alexander van Akkooi, MD, PhD
Associate Professor of Melanoma Surgical Oncology
Melanoma Institute Australia, University of Sydney
Sydney, Australia
Joshua Veatch, MD, PhD
Acting Assistant Professor, Division of Medical Oncology (UW); Physician (SCCA and UWM)
University of Washington/Seattle Cancer Care Alliance/UW Medicine
Seattle, WA
Michael Wong, MD, PhD
Department of Melanoma Medical Oncology, Division of Cancer Medicine
UT MD Anderson Cancer Center
Houston, TX
Faculty Photos
Wen Xu, MBBS (Hon), B med Sci, FRACP
Princess Alexandra Hospital, University of Queensland
Brisbane, Australia
Lisa Zaba, MD, PhD
Clinical Associate Professor, Dermatology; Director of the Merkel cell carcinoma (MCC) multi-disciplinary clinic
Stanford University
Stanford, CA

Monday, April 25, 2022
 
April 25-26, 2022

Registration & Breakfast
7:00AM - 7:35AM
Welcome Remarks & Course Intro
7:35AM - 7:40AM
Paul Nghiem, MD (Course Co-Chair)
CME Knowledge Assessment (ARS)
7:40AM - 7:45AM
State of the Field: Merkel Cell Carcinoma
7:45AM - 8:00AM
Paul Nghiem, MD
1. MCC Biology I
8:00AM - 9:40AM
Immunotherapy Platform and Related-omics
8:00AM - 8:20AM
Kenneth Tsai, MD, PhD
Animal Models of MCC
8:20AM - 8:40AM
Andrezj Dlugosz, MD
Mechanisms of Oncogenesis: MCC Cell of Origin
8:40AM - 9:00AM
Jurgen Becker, MD, PhD
Clues to the Origins of Merkel Cell Carcinoma
9:00AM - 9:20AM
Paul Harms, MD, PhD
Epigenetic and Genetic Determinants of Merkel Cell Carcinoma
9:20AM - 9:40AM
Isaac Brownell, MD, PhD
BREAK
9:40AM - 10:00AM
2. Treatment
10:00AM - 12:00PM
Surgery - Adjuvant RT
10:00AM - 10:20AM
Alexander van Akkooi, MD, PhD
Role of radiotherapy in Merkel cell cancer
10:20AM - 10:40AM
UPENDRA PARVATHANENI, MBBS, FRANZCR
Systemic therapies for metastatic Merkel cell carcinoma
10:40AM - 11:00AM
Sandra D'Angelo, MD
Neoadjuvant PD-1 Pathway Blockade for MCC: a window into treatment response and primary resistance
11:00AM - 11:20AM
Suzanne Topalian, MD
MCC Immunotherapy: Lessons Learnt and Unmet Needs
11:20AM - 11:40AM
Shailender Bhatia, MD
Treatment Discussion - Panel
11:40AM - 12:00PM
Shailender Bhatia, MD
Sandra D'Angelo, MD
UPENDRA PARVATHANENI, MBBS, FRANZCR
Suzanne Topalian, MD
Alexander van Akkooi, MD, PhD
LUNCH
12:00PM - 1:00PM
Poster Session {non-accredited}
12:50PM - 2:00PM
Merkel Cell Carcinoma in France: Characteristics of a Cohort of 1300 Patients
2:00PM - 2:12PM
Astrid Blom, MD
Featured Abstract: Virally mediated mechanisms of HLA class I loss in Merkel cell carcinoma and implications for viral epitope presentation
2:15PM - 2:30PM
Derin Keskin, PhD
3. Abstract Sessions
2:30PM - 3:42PM
Abstract: Merkel polyoma virus specific transgenic T cell receptor therapy in PD-1 inhibitor refractory Merkel cell carcinoma
2:30PM - 2:42PM
Joshua Veatch, MD, PhD
Abstract: Development of a Merkel polyomavirus-specific T cell receptor analysis tool to guide cancer immunotherapy
2:42PM - 2:54PM
Saumya Jani, B.S.
Abstract: MCPyV ALTO is silenced in virus-positive Merkel cell carcinoma and suppresses tumorigenesis
2:54PM - 3:06PM
Nick Salisbury, PhD
Abstract: Real-world assessment of ipilimumab plus nivolumab in anti-PD-L1/PD-1- refractory Merkel 1 Cell Carcinoma
3:06PM - 3:18PM
Sophia Shalhout, PhD
Abstract: Impact of duration of immunotherapy on clinical outcomes in advanced Merkel cell carcinoma patients responding to first-line immunotherapy
3:18PM - 3:30PM
Lisa Tachiki, MD
Abstract: The paranuclear dot in Merkel cell carcinoma, how does it form and what does it do?
3:30PM - 3:42PM
Natasha Hill, PhD
CME Knowledge Assessment (ARS)
3:45PM - 3:55PM
Closing Remarks
3:55PM - 4:05PM
Paul Nghiem, MD
ADJOURN
4:05PM - 4:10PM
MCC Symposium Photo
4:10PM - 4:20PM
Symposium Reception
6:00PM - 8:00PM
Tuesday, April 26, 2022
Sign In & Breakfast
7:00AM - 7:45AM
Welcome Remarks & Course Intro
7:45AM - 7:50AM
Paul Nghiem, MD
CME Knowledge Assessment (ARS)
7:50AM - 8:00AM
4. Clinical Trials
8:00AM - 9:00AM
Update on Australian MCC Clinical Trials
8:00AM - 8:10AM
Wen Xu, MBBS (Hon), B med Sci, FRACP
AST-008 and TLR9 agonists in Merkel cell carcinoma
8:10AM - 8:20AM
Sunandana Chandra, MD, MS
Randomized Phase II Study of NIVO + IPI vs. NIVO + IPI + SBRT in Metastatic or Recurrent Merkel Cell Carcinoma
8:20AM - 8:30AM
Sungjune Kim, MD, PhD
Ablative Radiation Therapy for Merkel Cell Carcinoma
8:30AM - 8:40AM
Christopher Barker, MD
Clinical Trials Discussion - Panel
8:40AM - 9:00AM
Christopher Barker, MD
Sunandana Chandra, MD, MS
Wen Xu, MBBS (Hon), B med Sci, FRACP
Sungjune Kim, MD, PhD
BREAK
9:00AM - 9:15AM
5. MCC Biology II
9:15AM - 10:35AM
Transcriptional Responses to Type II Interferon Treatment in Merkel cell carcinoma
9:15AM - 9:35AM
Richard Tothill, PhD
Can we harness T-cells specific for Merkel cell polyomavirus with therapuetic vaccination?
9:35AM - 9:55AM
David Koelle, MD
MCPyV-specific T cell discovery for adoptive T cell therapy
9:55AM - 10:15AM
Sine Hadrup, PhD
Contribution of Merkel Cell Polyomavirus to Merkel Cell Carcinoma
10:15AM - 10:35AM
James A. DeCaprio, MD
BREAK
10:35AM - 10:45AM
6. MCC Surveillance & Real-World Studies
10:45AM - 12:00PM
Cross-sectional Imaging In Merkel Cell Carcinoma: Is Less More?
10:45AM - 11:00AM
Vernon K. Sondak, MD
'Immunotherapy for solid organ transplant recipients with advanced MCC and other skin cancers
11:00AM - 11:15AM
Evan Lipson, MD
Diagnostic Yield of Staging Brain MRI in Merkel Cell Carcinoma
11:15AM - 11:30AM
David Miller, MD, PhD, FAAD
Real world management of MCC patients in France
11:30AM - 11:45AM
Mahtab Samimi, MD, PhD
Avelumab in mMMC: real-world data
11:45AM - 12:00PM
Margot Tesselaar, MD
CME Knowledge Assessment (ARS)
12:00PM - 12:10PM
LUNCH
12:10PM - 12:50PM
7. Panel Discussions
12:50PM - 3:20PM
Genomics and Novel Targets - Panel Discussion
12:50PM - 1:20PM
Kenneth Tsai, MD, PhD
James A. DeCaprio, MD
Isaac Brownell, MD, PhD
Denise Galloway, PhD
The Optimal Role of Radiation Therapy & Surgery - Panel Discussion
1:20PM - 1:50PM
UPENDRA PARVATHANENI, MBBS, FRANZCR
Emily Keung, MD
Socioeconomic and Racial Disparities in MCC - Panel Discussion
1:50PM - 2:20PM
Abbas Rattani, MD
Mackenzie Martin, BA
Kyle Lauck, MD, Resident Physician (PGY-1)
Ata Moshiri, MD, MPH (Facilitator)
Duration of Immunotherapy - Panel Discussion
2:20PM - 2:50PM
Shailender Bhatia, MD
Lisa Tachiki, MD
Lisa Zaba, MD, PhD
New Therapies on the Horizon - Panel Discussion
2:50PM - 3:20PM
David Koelle, MD
Paul Nghiem, MD
Michael Wong, MD, PhD
Closing Remarks
3:20PM - 3:35PM
Paul Nghiem, MD
Q&A Summary
3:35PM - 3:40PM

The University of Washington School of Medicine gratefully acknowledges receipt of an educational

grant in support of this Continuing Medical Education activity from:

 

Pfizer


Fred Hutch/University of Washington Cancer Consortium

GOLD TIER

Immunomic Therapeutics

Kartos Therapeutics

Merck

Natera

Rain Therapeutics

SILVER TIER

EMD Serono

For information on becoming an exhibitor for this in-person event, please contact Continuing Medical Education Conference Services at [email protected].


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Continuing Medical Education
School of Medicine | University of Washington
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